CBD Oil for Pain – Pain Management NEW Scientific Evidence

cbd oil for pain

CBD Oil For Pain

CBD oil for Pain is a buzz-generating word in the healthcare industry. As it is positively associated with treating several illnesses such as anxiety, chronic pain, and reduction of inflammation and offers feelings of relaxation and sleep support.

It is extracting CBD from the cannabis plant, such as industrial hemp and marijuana, as both plants contain cannabinoids with cloth carrying more of it. CBD or Cannabidiol is an active ingredient found in the cannabis plant that is associated with the prevention of the breakdown of the chemical in the brain that affects pain, mental function, and mood. Learn more about CBD.


The use of cannabis for pain management dates back to ancient China, as per a report issued in the journal Cannabis and Cannabinoid Research. However, most of the latest cannabinoids research is positive and is continually uncovering more and more beneficial influences on health.

Let’s review the scientific evidence for CBD For pain and its influence on pain management. 


Pain Management with CBD Oil

A study issued in the Journal of Experimental Medicine discovers that CBD Oil For Pain significantly reduced chronic inflammation and pain. While an assessment from Neurotherapeutics found that CBD Oil for Pain helps reduce anxiety in individuals with specific disorders. Similarly, results from a 2017 study show CBD to be useful for managing less acute pain and less intense pain for individuals with migraine.

A 2017 study issued in the journal Pain found that the application of topical CBD Oil for Pain helped impede the development of joint pain in subjects with osteoarthritis. A similar review published in the European Journal of Pain in year 2016, observed that topical CBD noticeably decreased joint swelling and assessment of pain and inflammation in rats with arthritis.

In a 2018 study issued in Pediatric Dermatology, scientists testified three cases of topical CBD, including oil, cream, and spray on children with a rare, blistering skin condition called epidermolysis bullosa. The results revealed fewer blisters, faster wound healing, and improvement of pain. In all three cases, while one child was entirely able to stop oral opioid analgesic pain medication without any adverse effects.

Another 2018 study published in the Cochrane Database of Systematic Reviews observed the use of cannabis-based medicines and found them to be beneficial in the treatment of chronic neuropathic pain. Somatosensory system triggering with damage, which often occurs in people with illnesses like diabetes and multiple sclerosis.


Cannabidiol for Cancer-Related Pain 

A comprehensive review conducted in 2018, expanding over studies conducted between 1975 and March 2018 examined various types of pain and CBD influence on them and found CBD Oil for Pain to be influential in pain management of:

  • Cancer pain
  • Neuropathic pain
  • Fibromyalgia


The studies found CBD to be effective in overall pain management without causing any adverse side effects.

The National Cancer Institute (NCI) has also pointed to CBD as a promising option for decreasing chemotherapy side effects, including pain, lack of appetite, and vomiting. In a 2010 research on cancer-related pain, the subjects were treated with oral sprays of a combination THC-CBD extract in conjunction with opioids.

The results revealed that usage of extract delivered more effective pain relief than consuming opioids alone.


  1. Baron EP. (2018). Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: An update on current evidence and cannabis science. DOI:
  2. Cannabinoids suitable for migraine prevention. (2017).
  3. Cannabis and cannabinoids (PDQ®) — health professional version. (2019).
  4. Ewing LE, et al. (2019). Hepatotoxicity of a cannabidiol-rich cannabis extract in the mouse model. DOI:
  5. Hammell, DC, et al. (2016). Transdermal cannabidiol reduces inflammation and pain-related behaviours in a rat model of arthritis. DOI:
  6. Iffland K, et al. (2017). An update on safety and side effects of cannabidiol: A review of clinical data and relevant animal studies. DOI:
  7. Johnson JR, et al. (2013). An open-label extension study to investigate the long-term safety and tolerability of THC/CBD Oromucosal spray and oromucosal THC spray in patients with terminal cancer-related pain refractory to strong opioid analgesics. DOI:
  8. Johnson JR, et al. (2010). Multicenter, double-blind, randomized, placebo-controlled, parallel-group study of the efficacy, safety, and tolerability of THC: CBD extract and THC extract in patients with intractable cancer-related pain. DOI:
  9. Simmerman E, et al. (2019). Cannabinoids as a potential new and novel treatment for melanoma: A pilot study in a murine model. DOI:
  10. Volkow ND. (2015). The biology and potential therapeutic effects of cannabidiol.
  11. Vučković S, et al. (2018). Cannabinoids and pain: New insights from old molecules. DOI:

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